MT-II Overview
MT-II is a synthetic peptide and investigational melanocortin receptor agonist. It is being studied in preclinical and controlled research models for melanin biosynthesis modulation.
Researchers may also study MT-II for receptor-mediated signaling and metabolic pathway regulation. In research models, MT-II is classified as a short-acting, engineered peptide analogue.
It is designed to mimic alpha-melanocyte-stimulating hormone (α-MSH) activity. Researchers believe that structural modifications in MT-II may enhance receptor binding affinity and potency in investigational systems.
Chemical Properties
| PubChem CID | 92432 |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | 1024.2 g/mol |
| Synonyms | MT-II, Melanotan-II, Melanotan 2… |
| 2D Structure |  |
| CAS | 121062-08-6 |
| IUPAC Name | (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide |
| Environmental precautions | Do not allow to enter sewers/ surface or ground water. |
| Hazards |  |
| SOLUBILITY | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1: |
Working Mechanism of MT-II
Researchers have observed the proposed working mechanism of MT-II in experimental models. They have noticed that MT-II may function as a melanocortin receptor agonist. It binds to melanocortin-type receptors and triggers intracellular signaling cascades.
When these receptors are activated, they modulate melanin synthesis pathways. This might influence peptide-mediated signaling networks and regulate cellular metabolic processes in research preclinical models.
Research Applications of MT-II
MT-II is studied in controlled laboratory models for its following potential research applications.
- Melanin Biosynthesis Studies
- Cellular Signaling and Receptor Pathway Studies
- Metabolic Pathway Regulation Investigations in investigational models
- Multi-Pathway Synergy Studies
Why Choose Purerawz for MT-II?
At Purerawz, every batch of MT-II is handled with strict quality control to ensure reliability for research purposes. However, users should independently verify documentation before research use.
All materials are packaged according to laboratory safety standards and shipped in compliance with applicable handling regulations.
Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use
Reference Links
- Gilhooley, E., Daly, S., & McKenna, D. (2021). MT-II User Experience: A Qualitative Study of Online Discussion Forums. Dermatology, 1–5. https://doi.org/10.1159/000514492
- Dorr, R. T., Lines, R., Levine, N., Brooks, C., Xiang, L., Hruby, V. J., & Hadley, M. E. (1996). Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sciences, 58(20), 1777–1784. https://doi.org/10.1016/0024-3205(96)00160-9
